Yes, the 22 inch wheels have lower-profile tires than the 20s. The ride is sportier on them thanks to less sidewall, but you’re still driving a body-on-frame vehicle, so the differences are not life-changing.
Not sure what you’re asking on the second part of your question… but if you’re asking if you can swap wheels/tires from 22s to 20s or vice-versa, the answer is yes.
